
In 2026, the Glenn Procedure is the critical second stage in the surgical reconstruction of a single-ventricle heart. Usually performed when an infant is between 4 and 6 months old, it prepares the body for the final Fontan procedure by reducing the workload on the heart's lone functioning ventricle.
Diagnosis of a single-ventricle heart defect (e.g., HLHS or Tricuspid Atresia)
Successful completion of the Stage 1 (Norwood) procedure
Infant age typically between 4 and 6 months
Signs that the infant is "outgrowing" the initial shunt (decreasing oxygen levels)
Sufficient growth and development of the pulmonary arteries
Connecting the superior vena cava (SVC) directly to the pulmonary artery
Allowing blood from the upper body to flow passively into the lungs
"Unloading" the single ventricle so it only pumps blood to the body, not the lungs
Increasing systemic oxygen levels and reducing cyanosis (blueness)
Providing a stable "bridge" to the final Fontan stage of reconstruction
Connection: The superior vena cava is detached from the heart and sewn to the pulmonary artery.
Shunt Removal: Any temporary shunts from the previous surgery are typically removed.
Lung Access: Blood from the head and arms is redirected to bypass the heart's right side.
Monitoring: Surgeons use real-time NIRS technology to ensure brain oxygenation.
Incision: Many 2026 cases use a partial sternotomy for faster healing and less pain.
Minimally Invasive Sternotomy: Smaller incisions lead to faster bone healing in infants.
Hemodynamic Simulation: AI-driven software predicts blood flow patterns for better precision.
Real-Time NIRS: Standard monitoring ensures the brain receives optimal oxygen throughout.
3D Echo Guidance: Enhanced imaging helps surgeons visualize the connection in real-time.
Specialized Post-Op Protocols: Focused care to manage the body's adjustment to new pressures.
Hospital Stay: Most infants stay in the Cardiac ICU for 5 to 7 days.
Pressure Adjustment: Temporary facial puffiness is common as the body adapts to new flow.
Pain Management: Modern protocols focus on infant comfort and faster extubation.
Growth Monitoring: Weight gain and oxygen levels are closely tracked post-surgery.
Next Steps: This is a bridge to the Fontan Procedure, usually performed at age 2 to 4.
Significantly reduces the strain and workload on the heart’s single ventricle
Improves skin color and energy levels by increasing blood oxygenation
Provides several years of circulatory stability for the growing child
Minimally invasive techniques in 2026 result in smaller scars and quicker recovery
Prepares the pulmonary arteries for the final stage of heart reconstruction